What is NAD+?
Nicotinamide adenine dinucleotide is a molecule, which is present in all human cells. And plays a vital role in the regulation of several biochemical reactions. For example, regulating signaling pathways, DNA repair, metabolism, cellular processes, and ageing. The research has found that when there is an increase in cellular energy levels, the NAD+ levels also increase. This cellular energy provides fuel for your life. And gives power to your brain, heart, protects against DNA damage, which can increase your longevity.
One more study has depicted that this molecule is also used to power metabolism and enable mitochondria (a power station of the cell), which converts food into energy that is used to sustain your all body functions. On the other hand, a decline in NAD+ levels impairs your body’s ability to synthesis cellular energy that is significant in promoting protection against DNA damage.
In your body, this molecule is produced by simple amino acids. Like tryptophan, food that contains nicotinic acid (NA), nicotinamide mononucleotide (NMN), nicotinamide riboside (NR), and other precursors.
Why do we age?
The research has shown that decline in NAD+ levels is the major contributor to ageing. There is a dramatic reduction in NAD+ in your skin (almost 50% decline) when you age.
Two more studies use MRI to determine the NAD+ age-related decline in the human brain. The first research, which is conducted in 2015, has shown that there is a clear decline in the intracellular NAD+ levels. And redox state in the brain like with ageing. The second research conducted in 2019 depicted that between the period of adulthood and old age there to 10 to 25% reduction in NAD+ levels in the human brain.
“The loss of NAD as we age, and the resulting decline in sirtuin activity, is thought to be a primary reason our bodies develop diseases when we are old but not when we are young.”
- David A. Sinclair,
Why do levels decline with age?
According to both animal and human studies. It is clear that NAD+ levels decrease with growing ages in blood and several tissues. But why does its level decline? There are several mechanisms, which have the potential to reduce these levels. Including sedentary lifestyle, stress, overconsumption, DNA damage, and illness.
A better understanding of what is NAD+
According to health experts, at a young age, there is a healthy supply in your body. Which keeps you vibrant, young, and maintains good health. This is because it gives a direct link between your cellular signaling and metabolism. Furthermore, it plays a crucial role in supporting your immune system, regulating the sleep cycle, and repairing DNA damage.
When the natural level of NAD+ decreases, your longevity also decreases. Low levels also increase the risk of several chronic diseases and make visible signs of ageing more prominent. But don’t worry! By focusing on natural steps you can easily boost your NAD+ levels every day. In return, this increase in NAD+ level promotes your overall health, physical energy, and youthful metabolism.
Tips to boost NAD+ levels to increase longevity
The more effective way to maintain adequate levels of NAD+ is to make required lifestyle changes. By following these changes in daily life you can make your NAD+ levels strong. And can maintain high energy levels and healthy metabolism. Read more about how to increase NAD+ naturally.